After I left university, I worked at Imperial College, London, on my invention the Droplet Reactor, a very early microfluidic device that I patented in the early 1980s. I applied a variant of this system to protein crystallization, and I worked with Professor David Blow – one of the well-known early crystallographers who worked with Max Perutz and others – to develop IMPAX, the first “robot” that was specifically designed for protein crystallization. In 1987, another Imperial scientist and I set up Douglas Instruments, and the company has made systems for automatic crystallization ever since. In 2011 I made a bet with a colleague in India that I could find biochemical evidence that respiratory viruses respond to temperature fluctuations, and I became interested in the seasonality and temperature sensitivity of respiratory viruses. In 2016 my paper on the topic was published in Medical Hypotheses.